HDx Therapy enabled by the Theranova dialyzer

One step closer to the natural kidney 1

Connect with us See the evidence

After transitioning to Theranova, we have seen an increase in our compliance and remaining for their entire treatments. ... you can really maximize your profits on your medication costs, on your hospitalizations.2-7 ... It made sense financially, it made sense for our clinic and for our quality measures. ... I feel like Theranova is a no-brainer.

Sarah Walls, RN, Director of Dialysis

Go beyond urea. One effortless dialyzer switch could make a world of difference for your patients.

Theranova 400 and 500

One step closer to the natural kidney1

HDx therapy enabled by Theranova dialyzers deliver superior removal of large-middle molecules compared to both conventional (high-flux) HD and HDF therapies, while maintaining stable serum albumin levels and without changing your current HD machines and workflow.8,9

See how the Theranova dialyzer works

Watch the video to see how the Theranova dialyzer brings us a step closer to the natural kidney.1

Theranova patient

Choosing the Theranova dialyzer may reduce hospitalizations, medication usage and cost of care compared to high-flux HD

  • Up to 45% reduction in all-cause hospitalizations2
  • Up to $4,772 lower cost per-patient, with savings demonstrated in 96% of the 10,000 simulations in a probability analysis of mean cost difference2
Randomized controlled trial of US hemodialysis patients
  • Reduced erythropoietin resistance and ESA utilization3-5,10
  • Decreased dosing of supportive medications such as iron, insulin and antihypertensive medications4,5
Multicenter, observational study; retrospective analysis; and prospective, randomized, controlled, open-label studies
Theranova patient

Patient-reported quality of life may improve using the Theranova dialyzer compared to high-flux HD

  • Improved effects and burden of kidney disease11
Prospective, multicenter, observational study
  • Improved sleep quality, energy level, and general well-being12
Single center, unblinded, exploratory pilot study

Up to 2.5 hours reduction in patient-reported dialysis recovery time13

Single center, retrospective analysis

Reduction in patient-reported pruritis14

Randomized, prospective, controlled, open-label study

Up to 55% reduction in patients meeting diagnostic criteria for restless leg syndrome (RLS)11

Prospective, multicenter, observational study

Hear from patients on their experiences with HDx therapy

" ... when I told (my doctor) about (my restless leg syndrome), she had the idea to switch me over to Theranova dialyzer. And after that, I got better. That was amazing. And I could finally sleep again. Sleep peacefully. All the symptoms have completely changed with the new dialyzer. It gave me a new lease of life. "


Andre, patient on HDx therapy

" I feel, in myself, Theranova definitely made an impact on my family life, home life and all parts of my life. I can do things that I couldn't do .. I go take my kids out to the park. "


Dennis, patient on HDx therapy

" When we started dialysis with the new Theranova Dialyzer, after a few weeks, like within 2 months, I can see that her itchiness has reduced by 90%, and after like four months, there is no itchiness, ... she doesn't scratch. ... That is like a result that you can see. "


Shatila, caregiver for mother on HDx therapy

" ... couple days after using it, ... I started to feel better ... I was eating a little better, and my sleep wasn't great, but it was way better, much improved. So, I thought, boy, this is ridiculous. Then I started thinking - wait a minute - this is not imaginary ... obviously there is a difference in the dialyzer. "


Robert, patient on HDx therapy

HDxcellence Academy

HDxcellence Academy

Access our on-demand video library of short (5-15 minutes) modules delivered by experts on topics such as:

MCO dialyzers like the Theranova dialyzer that bring us one step closer to the natural kidney1 

• Pathological role that conventional/large middle molecular toxins (up to 45 kDa) play in the development of uremic clinical syndrome  

• Evidence surrounding clinical effectiveness, safety and efficacy, patient-reported quality of life and health economic outcomes related to HDx therapy

The Theranova Dialyzer is indicated for patients with chronic kidney failure who are prescribed intermittent hemodialysis. It provides an expanded solute removal profile with increased removal of various middle molecules (up to 45 kDa) that may play a pathologic role in the uremic clinical syndrome. The Theranova Dialyzer is not intended for hemofiltration or hemodiafiltration therapy. The total extracorporeal blood volume for the Theranova Dialyzer and the set should represent less than 10% of the patient's blood volume.

For single use only.

Rx Only. For the safe and proper use of this device, refer to the Instructions for Use.


Baxter, HDx, MCO and Theranova are trademarks of Baxter International Inc. or its subsidiaries.